The relation of periodontal diseases to systemic diseases

<span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Background: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"...

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Bibliographic Details
Main Authors: Melanie Sadono Djamil (Author), Boedi Oetomo Roeslan (Author)
Format: Book
Published: Universitas Airlangga, 2008-12-01T00:00:00Z.
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Summary:<span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Background: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>The relationship between systemic disorders and periodontal disease has been studied extensively. With few </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>exceptions, it is more accurate to consider systemic diseases to be contributing factors in the pathogenesis of periodontal disease rather </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>than the primary etiologic factors. The development of periodontal disease cannot be separated from the weakening of immunologic </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>and immunopathological responses. Periodontal disease may enhance susceptibility to certain systemic diseases in several ways. </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>Lipopolysaccharide (LPS) and Gram-positive bacteria in the biofilm and proinflammatory cytokines produced from inflamed periodontal </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>tissues may enter the circulation system causing the development of certain systemic diseases. On the other hand, through immunologic </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>mediators, certain systemic disease may enhance susceptibility to periodontal disease caused by the decrease of immune responses </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>and the increase of proinflammatory cytokines. </em><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Purpose: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>The Purpose of this article is to review the immunologic aspect of two way </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>relationship between systemic diseases and periodontal diseases. </em><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Review</strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>: This review studied the relationship between general health </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>status, systemic diseases, and periodontal diseases through immunopathological responses and the weakening of the immune system </em><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>in the periodontal tissue. </em><span style="font-family: TribuneBold; font-size: 10pt; color: #231f20; font-style: normal; font-variant: normal;"><strong>Conclusion: </strong><span style="font-family: TribuneItalic; font-size: 9pt; color: #231f20; font-style: normal; font-variant: normal;"><em>there is a two-way relationship between periodontal diseases and systemic diseases.</em></span></span></span></span></span></span></span></span></span></span><br style="font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: 2; text-align: -webkit-auto; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px;" /></span></span></span></span></span></span></span></span>
Item Description:1978-3728
2442-9740
10.20473/j.djmkg.v41.i4.p167-172