Mechanisms underlying the relaxation by A484954, a eukaryotic elongation factor 2 kinase inhibitor, in rat isolated mesenteric artery

• Main Authors: Tomoko Kodama (Author), Muneyoshi Okada (Author), Hideyuki Yamawaki (Author)
• פורמט: ספר
• יצא לאור: Elsevier, 2018-05-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Eukaryotic elongation factor 2 kinase (eEF2K) is a calmodulin-related protein kinase which regulates protein translation. A484954 is an inhibitor of eEF2K. In the present study, we investigated the acute effects of A484954 on contractility of isolated blood vessels. Isometric contraction of rat isol...