Psoralen alleviates high glucose-induced HK-2 cell injury by inhibition of Smad 2 signaling via upregulation of microRNA 874

• Main Authors: Yongtao Lin (Author), Lili Zhong (Author), Hailun Li (Author), Yong Xu (Author), Xiang Li (Author), Donghui Zheng (Author)
• 格式: 圖書
• 出版: BMC, 2020-07-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Abstract Background Diabetic nephropathy (DN) causes the vast proportion of excess mortality for patients with diabetes. Novel therapeutic approaches slowing down its incidence is still lacking. Psoralen is the major active ingredient of Psoralea corylifolia Linn. (PCL), which was used to treat a nu...