Use of Eculizumab in Pediatric Patients With Transplant Associated Thrombotic Microangiopathy

• Main Authors: Laura Gomez-Ganda (Author), Maria Isabel Benitez-Carabante (Author), Aurora Fernandez-Polo (Author), Marina Muñoz-Lopez (Author), Berta Renedo-Miro (Author), Gema Ariceta (Author), Cristina Diaz De Heredia (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Transplant-associated thrombotic microangiopathy (TA-TMA) is a serious complication of hematopoietic stem cell transplantation (HSCT) associated with high morbidity and mortality. High-risk TA-TMA (hrTA-TMA) is characterized by multifactorial endothelial damage caused by environmental st...