Central Line-Associated Bloodstream Infections in Pediatric Intensive Care Unit

Introduction: The aim of this study was to determine the frequency of central line-associated bloodstream infections, risk factors, their relationship with catheter insertion location, and the effect of central line-associated bloodstream infections on mortality and pediatric intensive care unit (PI...

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Main Authors: Tanıl Kendirli (Author), Ayhan Yaman (Author), Çağlar Ödek (Author), Halil Özdemir (Author), Adem Karbuz (Author), Bilge Aldemir (Author), Haluk Güriz (Author), Can Ateş (Author), Gamze Özsoy (Author), Derya Aysev (Author), Ergin Çiftçi (Author), Erdal İnce (Author)
Format: Book
Published: Galenos Yayinevi, 2017-08-01T00:00:00Z.
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Summary:Introduction: The aim of this study was to determine the frequency of central line-associated bloodstream infections, risk factors, their relationship with catheter insertion location, and the effect of central line-associated bloodstream infections on mortality and pediatric intensive care unit (PICU) length of stay. Methods: This was a prospective, observational and cohort study, carried out between November 2009 and February 2011. During this period, all the patients who had central-line were monitored for central line-associated bloodstream infection. Results: In the study period, 275 patients were admitted to our PICU. The frequency of invasive device usage was 38.9% (107) for central venous catheter, 38.2% (105) for mechanical ventilation, 53.3% (147) for urinary catheter, and 11.3% (32) for artery line. Central line-associated bloodstream infection was detected in 16 (14.8%) of the patients and 23 central line-associated bloodstream infection attacks were observed. There were 14 central line-associated bloodstream infection attacks in 1.000 central venous catheter usage days. There were 168 patients without central venous catheter and 4 (2.4%) of them had blood stream infection. Thirty-six patients died and the mortality rate was 13%. Five of these patients (13.8%) died due to central line-associated bloodstream infection, 27 (25%) of them had central venous catheter and 9 (6%) of them did not (p=0.001). Conclusion: In conclusion, central line-associated bloodstream infection is one of the serious healthcare-associated infections, and it is an important cause of morbidity and mortality in PICUs.
Item Description:10.4274/cayd.86580
2146-2399
2148-7332