BAP1 mutations inhibit the NF-κB signaling pathway to induce an immunosuppressive microenvironment in uveal melanoma

Abstract Background Tumor immune microenvironment regulates the growth and metastasis of uveal melanoma (UM). This study aims to reveal the possible molecular mechanism of BRCA1-associated protein 1 (BAP1) mutations in affecting the tumor immune microenvironment in UM through mediating the nuclear f...

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Main Authors: Chao Zhang (Author), Shuai Wu (Author)
Format: Book
Published: BMC, 2023-09-01T00:00:00Z.
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