Mediating kinase activity in Ras-mutant cancer: potential for an individualised approach?
It is widely acknowledged that there is a considerable number of oncogenic mutations within the Ras superfamily of small GTPases which are the driving force behind a multitude of cancers. Ras proteins mediate a plethora of kinase pathways, including the MAPK, PI3K, and Ral pathways. Since Ras was co...
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| Main Authors: | , , , |
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| Format: | Book |
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Frontiers Media S.A.,
2024-09-01T00:00:00Z.
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