Hospital exposure as a risk factor for the transmission of measles: A case-control study in Turkey.

<p><strong>Objective:</strong> During a nationwide measles epidemic in 2013, we conducted an investigation in Sanliurfa province to assess risk factors for measles infections. <strong>Methods: </strong>In a case-control design, we compared the history of hospital exposu...

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Main Authors: Serap Çetin Çoban (Author), Selmur Topal (Author), Fehminaz Temel (Author), Muharrem Öncül (Author), Bao-ping Zhu (Author), Levent Akın (Author)
Format: Book
Published: Turkish Society of Public Health Specialists, 2016-05-01T00:00:00Z.
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Summary:<p><strong>Objective:</strong> During a nationwide measles epidemic in 2013, we conducted an investigation in Sanliurfa province to assess risk factors for measles infections. <strong>Methods: </strong>In a case-control design, we compared the history of hospital exposures for 189 randomly selected laboratory-confirmed patients (aged <15 years) residing in the central district and control-individuals matched for neighbourhood and age. We estimated the effectiveness of the vaccine (VE). <strong>Results:</strong>For infants from 0-11 months, 53.8% of the case and 23.8% of the controls had visited a hospital during one the month prior to the onset of the case's rash (ORadj=3.7, 95% CI=1.6-8.6). For children from 1-6 years, 48.2% of the cases  and 14.3% of the controls visited a hospital during one month prior to the onset case's rash (ORadj=5.5,95% CI=2.5-12.8) and  59.7% of cases had not completed one dose of measles vaccine  by 12 months, compared with </p><p>14.7% of controls (ORadj=7.4,95% CI=2.1-26.9; VE=86%,95% CI=52-96%). For children from 7- 14 years, 53.8% of the cases had not completed one dose of measles vaccination by age 12 months, compared with 15.4%  of controls (ORadj=6.7,95% CI=1.7-26.6; VE=85%, 95% CI=41-96%). <strong>Conclusion: </strong>We conclude that the hospitals facilitated measles transmission during this epidemic. We recommend triage febrile patients and patients with a rash in healthcare settings, and strengthening measles vaccination programme..</p><p><strong>Keywords:</strong> Measles; Measles Vaccine; Nosocomial Infections; Risk Factors; Case Control Study</p><p><strong><span style="font-family: Times New Roman; font-size: medium;"> </span></strong></p>
Item Description:1304-1088
1304-1096