Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2

• Main Authors: Catherine Z. Chen (Author), Paul Shinn (Author), Zina Itkin (Author), Richard T. Eastman (Author), Robert Bostwick (Author), Lynn Rasmussen (Author), Ruili Huang (Author), Min Shen (Author), Xin Hu (Author), Kelli M. Wilson (Author), Brianna M. Brooks (Author), Hui Guo (Author), Tongan Zhao (Author), Carleen Klump-Thomas (Author), Anton Simeonov (Author), Samuel G. Michael (Author), Donald C. Lo (Author), Matthew D. Hall (Author), Wei Zheng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Drug repurposing is a rapid approach to identify therapeutics for the treatment of emerging infectious diseases such as COVID-19. To address the urgent need for treatment options, we carried out a quantitative high-throughput screen using a SARS-CoV-2 cytopathic assay with a compound collection of 8...