Significance of the Vascular Concentration of Angiotensin II-Receptor Blockers on the Mechanism of Lowering Blood Pressure in Spontaneously Hypertensive Rats
To clarify the hypotensive mechanism of angiotensin II receptor-blockers (ARBs), drug concentrations in plasma and vascular tissues were measured using matrix-assisted laser desorption ionization time-of-flight mass spectrometry and imaging mass spectrometry. In spontaneously hypertensive rats, syst...
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| Main Authors: | , , , , |
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| Format: | Book |
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Elsevier,
2013-01-01T00:00:00Z.
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