Mammary like gland adenoma with GATA-3 expression - a benign vulval tumor with mammary differentiation often misdiagnosed as adenocarcinoma
Papillary hidradenoma/ mammary-like gland adenoma (MLGA) is a benign glandular tumor of the vulva. It presents as a mass lesion which often undergoes secondary ulceration and bleeding resembling a malignant tumor. It arises from specialized anogenital glands in the labial folds which resemble mammar...
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Barpeta Obstetrics and Gynaecological Society,
2021-07-01T00:00:00Z.
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| LEADER | 00000 am a22000003u 4500 | ||
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| 001 | doaj_704ba7b6a898482892a0a9968b98a4e7 | ||
| 042 | |a dc | ||
| 100 | 1 | 0 | |a Deval Parekh |e author |
| 700 | 1 | 0 | |a Sunaina Wadhwa |e author |
| 700 | 1 | 0 | |a Asima Mukhopadhyay |e author |
| 700 | 1 | 0 | |a Angad Singh |e author |
| 245 | 0 | 0 | |a Mammary like gland adenoma with GATA-3 expression - a benign vulval tumor with mammary differentiation often misdiagnosed as adenocarcinoma |
| 260 | |b Barpeta Obstetrics and Gynaecological Society, |c 2021-07-01T00:00:00Z. | ||
| 500 | |a 10.21276/obgyn.2021.8.1.28 | ||
| 500 | |a 2454-2334 | ||
| 500 | |a 2454-2342 | ||
| 520 | |a Papillary hidradenoma/ mammary-like gland adenoma (MLGA) is a benign glandular tumor of the vulva. It presents as a mass lesion which often undergoes secondary ulceration and bleeding resembling a malignant tumor. It arises from specialized anogenital glands in the labial folds which resemble mammary glands on microscopy. The tumour shows a tubulo-papillary architecture and is composed of bland columnar cells with apical snouting. GATA-3 is a transcription factor and it's expression is essential for normal mammary gland development. GATA-3 immunohistochemistry (IHC) is positive in luminal cells of breast and its positive in ductal hyperplasia as well as in breast carcinoma. In summary, we describe a case of a benign vulval mammary gland like adenoma with diffuse GATA-3 expression which was originally diagnosed as a malignant low-grade polymorphous adenocarcinoma and discuss its clinical and associated histopathological findings. | ||
| 546 | |a EN | ||
| 690 | |a mammary like gland adenoma | ||
| 690 | |a papillary hidradenoma | ||
| 690 | |a vulva | ||
| 690 | |a gata-3 | ||
| 690 | |a Gynecology and obstetrics | ||
| 690 | |a RG1-991 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n New Indian Journal of OBGYN, Vol 8, Iss 1, Pp 143-145 (2021) | |
| 787 | 0 | |n https://journal.barpetaogs.co.in/pdf/08143.pdf | |
| 787 | 0 | |n https://doaj.org/toc/2454-2334 | |
| 787 | 0 | |n https://doaj.org/toc/2454-2342 | |
| 856 | 4 | 1 | |u https://doaj.org/article/704ba7b6a898482892a0a9968b98a4e7 |z Connect to this object online. |