Nitroaromatics as hypoxic cell radiosensitizers: A 2D-QSAR approach to explore structural features contributing to radiosensitization effectiveness
Hypoxia is the prime component of tumor microenvironment that plays a pivotal role in cancer progression. Nitroaromatic compounds are known to enhance the sensitivity of hypoxic cells to ionizing radiation. The application of computational tools like Quantitative Structure-Activity Relationship (QSA...
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Elsevier,
2022-04-01T00:00:00Z.
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