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The Therapeutic Benefit of Allopurinol in the Treatment of Foreign Body Granulomas Caused by Polymethylmethacrylate Microspheres

Injectable polymethylmethacrylate (PMMA) microspheres are nonbiodegradable and too large for macrophage phagocytosis. There are several complications possible to happen, like chronic nonspecific inflammatory reactions, lip stiffness, infection, and granulomas. The occurrence of granulomas can lead t...

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Bibliographic Details
Main Authors: Luisa Kelmer Côrtes de Barros Silveira (Author), Felipe Ladeira de Oliveira (Author), Thais de Barros Castro Alves (Author), Maria Lourdes Candela Rambaldi (Author), Felipe Cupertino de Andrade (Author), Santuzza de Carvalho Kelmer (Author), Fabio Cuiabano Barbosa (Author)
Format: Book
Published: Hindawi Limited, 2012-01-01T00:00:00Z.
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Summary:Injectable polymethylmethacrylate (PMMA) microspheres are nonbiodegradable and too large for macrophage phagocytosis. There are several complications possible to happen, like chronic nonspecific inflammatory reactions, lip stiffness, infection, and granulomas. The occurrence of granulomas can lead to a not aesthetic result, making some extreme changes in the patient's life. The objective of this case report is to describe the successful treatment of foreign body granulomas caused by polymethylmethacrylate microspheres using allopurinol, an innovative therapy for this condition.
Item Description:2090-6463
2090-6471
10.1155/2012/945205

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