Effects of methotrexate upon inflammatory parameters induced by carrageenan in the mouse model of pleurisy

Background: The model of pleurisy induced by carrageenan exhibits a biphasic response (4 and 48 h) and permits the quantification of exudate, cell migration and certain enzymes such as myeloperoxidase (MPO) and adenosine-deaminase (ADA) that are markers of activated leukocytes.

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Bibliographic Details
Main Authors: Eduardo Monguilhott Dalmarco (Author), Tânia Silvia Fröde (Author), Yara Santos Medeiros (Author)
Format: Book
Published: Hindawi Limited, 2002-01-01T00:00:00Z.
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Summary:Background: The model of pleurisy induced by carrageenan exhibits a biphasic response (4 and 48 h) and permits the quantification of exudate, cell migration and certain enzymes such as myeloperoxidase (MPO) and adenosine-deaminase (ADA) that are markers of activated leukocytes.
Item Description:0962-9351
1466-1861
10.1080/09629350210000015700