Pathogenomic inference of virulence-associated genes in Leptospira interrogans.

• Main Authors: Jason S Lehmann (Author), Derrick E Fouts (Author), Daniel H Haft (Author), Anthony P Cannella (Author), Jessica N Ricaldi (Author), Lauren Brinkac (Author), Derek Harkins (Author), Scott Durkin (Author), Ravi Sanka (Author), Granger Sutton (Author), Angelo Moreno (Author), Joseph M Vinetz (Author), Michael A Matthias (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Leptospirosis is a globally important, neglected zoonotic infection caused by spirochetes of the genus Leptospira. Since genetic transformation remains technically limited for pathogenic Leptospira, a systems biology pathogenomic approach was used to infer leptospiral virulence genes by whole genome...