Antimicrobial Activity of <i>Origanum vulgare</i> Essential Oil against <i>Staphylococcus aureus</i> and <i>Escherichia coli</i>

• Main Authors: Sonia Tejada-Muñoz (Author), Denny Cortez (Author), Jesús Rascón (Author), Segundo G. Chavez (Author), Aline C. Caetano (Author), Rosa J. Díaz-Manchay (Author), Julio Sandoval-Bances (Author), Sonia Huyhua-Gutierrez (Author), Lizandro Gonzales (Author), Stella M. Chenet (Author), Rafael Tapia-Limonchi (Author)
• Format: Book
• Published: MDPI AG, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

<b>Background/Objectives</b>: <i>Oreganum vulgare</i> essential oil (OEO) is safe, effective, multifunctional, and widely used. This study aimed to evaluate OEO's chemical composition and antimicrobial activity in vitro against <i>S. aureus</i> and <i>E. coli</i>. <b>Methods</b>: The composition of OEO was determined by gas chromatography-mass spectrometry (GC-MS). <b>Results</b>: Compounds included monoterpenes with known antimicrobial activity, such as 2-menthen-1-ol (36.33%), linalyl acetate (9.26%), terpinene-4-ol (9.01%), 4-thujanol (6.33%), menthen (5.81%), sabinene (5.18%), and carvacrol methyl ether (5.14%). <b>Conclusions</b>: OEO had a strong antimicrobial activity with a minimum inhibitory concentration (MIC) of 1.90 mg/mL for <i>S. aureus</i> and 0.49 mg/mL for <i>E. coli</i> after 18 h incubation. The minimum bactericidal concentration (MBC) was 7.9 mg/mL against <i>S. aureus</i> and 0.99 mg/mL against <i>E. coli</i>. Thus, OEO could be used as a natural antimicrobial against <i>S. aureus</i> and <i>E. coli</i> infections.

Item Description

10.3390/ph17111430
1424-8247