Randomized comparative clinical trial of artemisia sieberi 5% lotion and clotrimazole 1% lotion for the treatment of pityriasis versicolor
<b>Aims:</b> To compare the therapeutic effects of topical Artremisia sieberi 5% lotion with topical clotrimazole 1% lotion in the treatment of pityriasis versicolor. <b> Materials and Methods:</b> 100 patients with pityriasis versicolor and microscopic...
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| Main Authors: | , , , |
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| Format: | Book |
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Wolters Kluwer Medknow Publications,
2008-01-01T00:00:00Z.
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| Summary: | <b>Aims:</b> To compare the therapeutic effects of topical Artremisia sieberi 5% lotion with topical clotrimazole 1% lotion in the treatment of pityriasis versicolor. <b> Materials and Methods:</b> 100 patients with pityriasis versicolor and microscopic identification of Malassezia furfur were randomly assigned to treatment with either topical Artemisia sieberi 5% lotion (group 1) or topical clotrimazole 1% lotion (group 2) for 2 weeks. Group 1 and group 2 consisted of 51 and 49 patients respectively. The patients were evaluated both clinically and mycologically at baseline and every 2 weeks for a period of 4 weeks. <b> Results: </b> At the end of the second week, clinical cure rates were 86.3% and 65.3% for group 1 and group 2 respectively (<i> P</i> < 0.01), but at the same time mycological cure rate was 92.2% for group 1 and 73.5% for group 2 (<i> P</i> < 0.05). At the end of the fourth week, clinical cure rates were 86.3% and 59.2% for group 1 and group 2 respectively (<i> P</i> < 0.01), and at the same time mycologic cure rate was 96.1% for group 1 and 65.3% for group 2 (<i> P</i> < 0.01). <b> Conclusions:</b> The results of this study demonstrated that Artemisia sieberi 5% lotion was more effective than clotrimazole 1% lotion in the treatment of pityriasis versicolor. |
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| Item Description: | 0019-5154 1998-3611 |