Radiation Type- and Dose-Specific Transcriptional Responses across Healthy and Diseased Mammalian Tissues

• Main Authors: Eftychia Sagkrioti (Author), Gökay Mehmet Biz (Author), Işıl Takan (Author), Seyedehsadaf Asfa (Author), Zacharenia Nikitaki (Author), Vassiliki Zanni (Author), Rumeysa Hanife Kars (Author), Christine E. Hellweg (Author), Edouard I. Azzam (Author), Stella Logotheti (Author), Athanasia Pavlopoulou (Author), Alexandros G. Georgakilas (Author)
• Format: Bog
• Udgivet: MDPI AG, 2022-11-01T00:00:00Z.
• Fag: article
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Ionizing radiation (IR) is a genuine genotoxic agent and a major modality in cancer treatment. IR disrupts DNA sequences and exerts mutagenic and/or cytotoxic properties that not only alter critical cellular functions but also impact tissues proximal and distal to the irradiated site. Unveiling the...