The Potential Antipyretic Mechanism of Gardeniae Fructus and Its Heat-Processed Products With Plasma Metabolomics Using Rats With Yeast-Induced Fever

• Main Authors: Xue Zhang (Author), Yun Wang (Author), Shaojing Li (Author), Yejia Dai (Author), Xiaoqing Li (Author), Qinghao Wang (Author), Guoyou Wang (Author), Yinlian Ma (Author), Xuezhu Gu (Author), Cun Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gardeniae Fructus (GF), prepared GF (GFP), and carbonized GF (GFC) are widely used in China for the treatment of fever. However, the involved antipyretic mechanism has not been fully elucidated. In this study, rectal temperature and pyrogenic cytokines were used to evaluate the antipyretic effect of...