Antivirals for adult patients hospitalised with SARS-CoV-2 infection: a randomised, phase II/III, multicentre, placebo-controlled, adaptive study, with multiple arms and stages. COALITION COVID-19 BRAZIL IX - REVOLUTIOn trialResearch in context

• প্রধান লেখক: Israel S. Maia (লেখক), Aline Marcadenti (লেখক), Viviane C. Veiga (লেখক), Tamiris A. Miranda (লেখক), Samara P.C. Gomes (লেখক), Mariana B.S. Carollo (লেখক), Karina L. Negrelli (লেখক), Jackeline O. Gomes (লেখক), Lucas Tramujas (লেখক), Erlon O. Abreu-Silva (লেখক), Glauco A. Westphal (লেখক), Ruthy P. Fernandes (লেখক), Jacques G.A. Horta (লেখক), Deborah C. Oliveira (লেখক), Uri A.P. Flato (লেখক), Ricardo C.R. Paoliello (লেখক), Camilo Fernandes (লেখক), Cássio L. Zandonai (লেখক), Juliana C. Coelho (লেখক), Waldemar C. Barros (লেখক), Juliana C. Lemos (লেখক), Renata S. Bolan (লেখক), Marcela M. Dutra (লেখক), Otavio C.E. Gebara (লেখক), Ana T.A. Lopes (লেখক), Meton S. Alencar Filho (লেখক), Jussara A. Arraes (লেখক), Victor A. Hamamoto (লেখক), Mauro E. Hernandes (লেখক), Nicole A. Golin (লেখক), Tiago M. Santos (লেখক), Renato H.N. Santos (লেখক), Lucas P. Damiani (লেখক), Fernando G. Zampieri (লেখক), João Gesto (লেখক), Flávia R. Machado (লেখক), Régis G. Rosa (লেখক), Luciano C.P. Azevedo (লেখক), Alvaro Avezum (লেখক), Renato D. Lopes (লেখক), Thiago M.L. Souza (লেখক), Otávio Berwanger (লেখক), Alexandre B. Cavalcanti (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2023-04-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Summary: Background: Repurposed drugs for treatment of new onset disease may be an effective therapeutic shortcut. We aimed to evaluate the efficacy of repurposed antivirals compared to placebo in lowering SARS-CoV2 viral load of COVID-19 patients. Methods: REVOLUTIOn is a randomised, parallel, blin...