Drug Transport across Porcine Intestine Using an Ussing Chamber System: Regional Differences and the Effect of P-Glycoprotein and CYP3A4 Activity on Drug Absorption
Drug absorption across viable porcine intestines was investigated using an Ussing chamber system. The apparent permeability coefficients, <i>P<sub>app,pig</sub></i>, were compared to the permeability coefficients determined in humans in vivo, <i>P<sub>eff,human<...
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Main Authors: | Yvonne E. Arnold (Author), Julien Thorens (Author), Stéphane Bernard (Author), Yogeshvar N. Kalia (Author) |
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Format: | Book |
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MDPI AG,
2019-03-01T00:00:00Z.
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