Systematic exploration of predicted destabilizing nonsynonymous single nucleotide polymorphisms (nsSNPs) of human aldehyde oxidase: A Bio‐informatics study
Abstract Aldehyde Oxidase (hAOX1) is a cytosolic enzyme involved in the metabolism of drugs and xenobiotic compounds. The enzyme belongs to the xanthine oxidase (XO) family of Mo containing enzyme and is a homo‐dimer of two 150 kDa monomers. Nonsynonymous Single Nucleotide Polymorphisms (nsSNPs) of...
Saved in:
Main Authors: | Catarina Coelho (Author), Jayaraman Muthukumaran (Author), Teresa Santos‐Silva (Author), Maria João Romão (Author) |
---|---|
Format: | Book |
Published: |
Wiley,
2019-12-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Bioinformatic Analysis of Deleterious Non-Synonymous Single Nucleotide Polymorphisms (nsSNPs) in the Coding Regions of Human Prion Protein Gene (PRNP)
by: Kourosh Bamdad, et al.
Published: (2016) -
Xanthine oxidase and aldehyde oxidase contribute to allopurinol metabolism in rats
by: Yoshitaka Tayama, et al.
Published: (2022) -
Cytokine Expression Patterns and Single Nucleotide Polymorphisms (SNPs) in Patients with Chronic Borreliosis
by: Tabea M. Hein, et al.
Published: (2019) -
CLC-2 single nucleotide polymorphisms (SNPs) as potential modifiers of cystic fibrosis disease severity
by: Bleecker Eugene R, et al.
Published: (2004) -
Transfer learning enhanced graph neural network for aldehyde oxidase metabolism prediction and its experimental application
by: Jiacheng Xiong, et al.
Published: (2024)