Transdermal Delivery of High Molecular Weight Antibiotics to Deep Tissue Infections via Droplette Micromist Technology Device (DMTD)

• Main Authors: Lakshmi Pulakat (Author), Howard H. Chen (Author), Madhavi P. Gavini (Author), Lauren A. Ling (Author), Yinian Tang (Author), Alexander Mehm (Author), Gregory L. Martin (Author), Corinna N. Beale (Author), Brian P. Mooney (Author), Hongmin Sun (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Wound infection by multidrug-resistant (MDR) bacteria is a major disease burden. Systemic administration of broad-spectrum antibiotics colistin methanesulfonate (CMS) and vancomycin are the last lines of defense against deep wound infections by MDR bacteria. However, systemic administration of CMS a...