Utilizing cell-free DNA to validate targeted disruption of MYO7A in rhesus macaque pre-implantation embryos
Direct injection of CRISPR/Cas9 into zygotes enables the production of genetically modified nonhuman primates (NHPs) essential for modeling specific human diseases, such as Usher syndrome, and for developing novel therapeutic strategies. Usher syndrome is a rare genetic disease that causes loss of h...
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Main Authors: | Junghyun Ryu (Author), Fernanda C. Burch (Author), Emily Mishler (Author), Martha Neuringer (Author), Jon D. Hennebold (Author), Carol Hanna (Author) |
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Format: | Book |
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The Korean Society of Animal Reproduction and Biotechnology,
2022-12-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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