Liver Cirrhosis of the Viral Etiology in Children

• Main Authors: F. I. Inoyatova (Author), G Z. Inogamova (Author)
• Format: Book
• Published: LLC "Diagnostics and Vaccines", 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.
• Notes: 2072-8107; 10.22627/2072-8107-2018-17-4-29-33
• Keywords: liver cirrhosis; etiology; hdv infection; children; Pediatrics; RJ1-570
• Source: Детские инфекции (Москва), Vol 17, Iss 4, Pp 29-33 (2018)

The structure of liver cirrhosis (LC) in children of Uzbekistan was studied. 135 children with viral etiology of liver cirrhosis at the age of 7-15 years of life were examined. It was established that in the structure of viral liver cirrhosis in children, mixed etiology prevails (77.1%) with a predominance of HDV infection (B + C + D - 35.6% and B + D - 23.7%). Mixed infection is considered as a predictor of disease progression, especially in cases of overlap of HDV infection, which was also expressed by the frequent identification of the decompensated stage of the liver cirrhosis C-class of Child-Pugh and complications. Levels of N-terminal propeptides and C-terminal telopeptides of type I collagen in children with liver cirrhosis can serve as markers of compensation and progression of the disease.