A governance of ion selectivity based on the occupancy of the "beacon" in one- and four-domain calcium and sodium channels
ABSTRACTOne of nature's exceptions was discovered when a Cav3 T-type channel was observed to switch phenotype from a calcium channel into a sodium channel by neutralizing an aspartate residue in the high field strength (HFS) +1 position within the ion selectivity filter. The HFS+1 site is dubbe...
Saved in:
Main Author: | J. David Spafford (Author) |
---|---|
Format: | Book |
Published: |
Taylor & Francis Group,
2023-12-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Editorial: Structure Related Druggability of Voltage-Gated Sodium and Calcium Ion-Channels to Treat Diseases
by: Tamer M. Gamal El-Din, et al.
Published: (2022) -
Roles for Countercharge in the Voltage Sensor Domain of Ion Channels
by: James R. Groome, et al.
Published: (2020) -
S100 Calcium-Binding Proteins and Ion Channels
by: Anton eHermann, et al.
Published: (2012) -
The Roles of Calcium Ions in Parkinson's Disease: Calcium Channel Inhibitors as a Novel Agents?
by: Md Reyaz Alam, et al.
Published: (2022) -
Sodium-calcium exchanger and multiple sodium channel isoforms in intra-epidermal nerve terminals
by: Gasser Andreas, et al.
Published: (2010)