Rare case of phenytoin induced acute generalized exanthematous pustulosis with cerebellar syndrome

Acute generalized exanthematous pustulosis (AGEP) is a rare drug induced cutaneous hypersensitivity reaction characterized by sudden onset of fever with sterile pustules overlying an erythematous skin occurring all over the body. The offending drugs are usually B-lactams and macrolides.Among anticon...

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Bibliographic Details
Main Authors: Pravin U Shingade (Author), Vaishali Wankhede (Author), Pritam S Kataria (Author), Nitin Sonone (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2014-01-01T00:00:00Z.
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Summary:Acute generalized exanthematous pustulosis (AGEP) is a rare drug induced cutaneous hypersensitivity reaction characterized by sudden onset of fever with sterile pustules overlying an erythematous skin occurring all over the body. The offending drugs are usually B-lactams and macrolides.Among anticonvulsants carbamazepine and Phenobarbital are commonly associated with AGEP. Only one case of phenytoin induced AGEP has been reported in literature. We present a rare case of AGEP with cerebellar syndrome occurring after receiving loading dose of phenytoin.
Item Description:0019-5154
1998-3611
10.4103/0019-5154.127715