Carbon Nanotubes-Potent Carriers for Targeted Drug Delivery in Rheumatoid Arthritis

• Główni autorzy: Camilla Kofoed Andersen (Autor), Sangita Khatri (Autor), Jonas Hansen (Autor), Sofie Slott (Autor), Rohith Pavan Parvathaneni (Autor), Ana C. Mendes (Autor), Ioannis S. Chronakis (Autor), Shu-Chen Hung (Autor), Narendiran Rajasekaran (Autor), Zhuoran Ma (Autor), Shoujun Zhu (Autor), Hongjie Dai (Autor), Elizabeth D. Mellins (Autor), Kira Astakhova (Autor)
• Format: Książka
• Wydane: MDPI AG, 2021-03-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Two types of single-walled carbon nanotubes (SWCNTs), HiPco- and carboxyl-SWCNT, are evaluated as drug carriers for the traditional anti-inflammatory drug methotrexate (MTX) and a small interfering RNA (siRNA) targeting NOTCH1 gene. The nanotubes are solubilized by PEGylation and covalently loaded w...