Alendronate prevents angiotensin II-induced collagen I production through geranylgeranylation-dependent RhoA/Rho kinase activation in cardiac fibroblasts
Collagen I is the main component of extracellular matrix in cardiac fibrosis. Our previous studies have reported inhibition of farnesylpyrophosphate synthase prevents angiotensin II-induced cardiac fibrosis, while the exact molecular mechanism was still unclear. This paper was designed to investigat...
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| Main Authors: | , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2015-12-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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