Accuracy of 64-multidetector computed tomography in diagnosis of adnexal tumors

<p>Abstract</p> <p>Background</p> <p>Adnexal cancers are in fifth place among the tumors with the highest mortality in the female population. The aim of the present study was to evaluate the accuracy of Multi-detector computed tomography (MDCT) on a 64-multislice CT sca...

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Main Authors: Gatreh-Samani Fatemeh (Author), Tarzamni Mohammad (Author), Olad-Sahebmadarek Elaheh (Author), Dastranj Ali (Author), Afrough Aimaz (Author)
Format: Book
Published: BMC, 2011-08-01T00:00:00Z.
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Summary:<p>Abstract</p> <p>Background</p> <p>Adnexal cancers are in fifth place among the tumors with the highest mortality in the female population. The aim of the present study was to evaluate the accuracy of Multi-detector computed tomography (MDCT) on a 64-multislice CT scanner in the detection and differentiation of adnexal masses stages.</p> <p>Methods</p> <p>During the present prospective study, 95 women with a primary diagnosis of ovarian mass in base of clinical examination and ultrasonographic findings underwent preoperative evaluation by a 64-slice MDCT with a section thickness of 0.6 mm, 50% overlap and reconstructed images. Afterward, results of MDCT were compared with surgical and histopathological findings, and the sensitivity, specificity, positive and negative predictive value and accuracy were determined.</p> <p>Results</p> <p>The mean age of patients was 48.63 ± 13.93 years. MDCT diagnosed 25 (26.3%) masses to be benign and 70 (73.7%) to be malignant (sensitivity, specificity, positive and negative predictive value and accuracy were 92.8%, 88.0%, 95.5%, 81.4% and 91.5% respectively). The sensitivity and specificity of MDCT in determining local extension was 72.2% and 93.4% respectively. And the sensitivity and specificity of MDCT in determining peritoneal seeding and liver extension was 81.8% and 93% respectively. Estimated stage was significantly agreed with the surgical (Cohen's Kappa (κ) = 0.891) and histopathological findings (κ = 0.858).</p> <p>Conclusion</p> <p>MDCT is a highly sensitive and specific diagnostic method in evaluation of adnexal masses and successfully stage the tumor in consistent with surgery and histopathology.</p>
Item Description:10.1186/1757-2215-4-15
1757-2215