Congenital Diaphragmatic Hernia, Predictors of Survival and Adverse Outcomes

• Main Authors: Kamal Ali MD (Author), Nemer Aljuaid MD (Author), Saleh S. Algarni PhD (Author), Abadi Ghazwani BS (Author), Saad Alshreedah BS (Author), Nawaf Alghamdi MD (Author), Mohamad Alreefi MD (Author), Abdurhman Alsaif MD (Author), Naif Alotaibi BS (Author), Wejdan Alzahrani MD (Author), Saif Alsaif MD (Author)
• Format: Book
• Published: SAGE Publishing, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary

Objective. To examine the postnatal predictors of survival and adverse outcome among Congenital Diaphragmatic Hernia (CDH) infants. Method. Six-year retrospective review of CDH infants born at tertiary neonatal unit. Results. Forty infants with CDH were included; 27 (67.5%) survived to discharge. Non-survivors had a higher best, mean, and highest oxygenation index (OI) ( P  < .001) on day 1 compared to survivors. Best (AUC = 0.917), mean (AUC = 0.945), and highest (AUC = 0.923) OI on day 1 were all predictive of mortality. The mean day-1 OI had a significant correlation with the duration of ventilation (DOV) (Spearman rho correlation coefficient ( r S ) = .549, P  = .004), TTS ( r S  = .526, P  = .007), and the length of hospital stay (LOS) ( r S  = .497, P  = .012). The best and highest day-1 OI also correlated significantly with DOV, TTS, and LOS. Conclusion. First day OIs were excellent predictors of survival and have a significant correlation with the DOV, LOS, and TTS in infants with CDH.

Item Description

2333-794X
10.1177/2333794X241263760