The Effects of Inhaled β-Adrenergic Agonists in Transient Tachypnea of the Newborn
Aim . To investigate the efficacy of an inhaled β-adrenergic agonists in transient tachypnea of the newborn (TTN). Method . We retrospectively analyzed a cohort of 51 term infants (Group 1) and 37 term infants (Group 2) monitored in the newborn intensive care unit diagnosed with TTN. Infants in Grou...
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| Main Authors: | , , , , , |
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| Format: | Book |
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SAGE Publishing,
2016-05-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | Aim . To investigate the efficacy of an inhaled β-adrenergic agonists in transient tachypnea of the newborn (TTN). Method . We retrospectively analyzed a cohort of 51 term infants (Group 1) and 37 term infants (Group 2) monitored in the newborn intensive care unit diagnosed with TTN. Infants in Group 1 received humidified oxygen alone, and infants in Group 2 were administered the inhaled β-2 agonist plus humidified oxygen. Results . TTN clinical respiratory assessment, respiratory rate, oxygen saturation values, need for supplemental oxygen therapy, blood gas PH, PO 2 , and duration of hospitalization were significantly improved in infants in Group 2 as compared with infants in Group 1 ( P < .05). No statistically significant difference was observed with regard to blood glucose, potassium, heart rate, and PCO 2 ( P > .05). Conclusion . Inhaled β-adrenergic agonist added to humidified oxygen was found to improve clinical and laboratory parameters. We believe that further studies should be conducted with larger groups to demonstrate the efficacy of β-2 agonists in TTN patients. |
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| Item Description: | 2333-794X 10.1177/2333794X16645258 |