MSC-derived exosomes attenuate hepatic fibrosis in primary sclerosing cholangitis through inhibition of Th17 differentiation

• Main Authors: Wenyi Chen (Author), Feiyan Lin (Author), Xudong Feng (Author), Qigu Yao (Author), Yingduo Yu (Author), Feiqiong Gao (Author), Jiahang Zhou (Author), Qiaoling Pan (Author), Jian Wu (Author), Jinfeng Yang (Author), Jiong Yu (Author), Hongcui Cao (Author), Lanjuan Li (Author)
• Format: Book
• Published: Elsevier, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Primary sclerosing cholangitis (PSC) is an autoimmune cholangiopathy characterized by chronic inflammation of the biliary epithelium and periductal fibrosis, with no curative treatment available, and liver transplantation is inevitable for end-stage patients. Human placental mesenchymal stem cell (h...