Disseminated fusariosis in a patient with bone marrow aplasia,

Abstract Fusariosis is a superficial or systemic infection, which occurs mainly in immunocompromised hosts, especially in patients with hematological neoplasia; 70%-75% of the cases present cutaneous manifestations. The disseminated form is rare and difficult to diagnose; even with specific treatmen...

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Main Authors: Danielle Ferreira Chagas (Author), Lucia Martins Diniz (Author), Elton Almeida Lucas (Author), Paulo Sergio Emerich Nogueira (Author)
Format: Book
Published: Sociedade Brasileira de Dermatologia, 2020-11-01T00:00:00Z.
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Summary:Abstract Fusariosis is a superficial or systemic infection, which occurs mainly in immunocompromised hosts, especially in patients with hematological neoplasia; 70%-75% of the cases present cutaneous manifestations. The disseminated form is rare and difficult to diagnose; even with specific treatment, the evolution is usually fatal. Currently, it is considered an emerging disease; in some centers, it is the second most common cause of invasive mycosis, after aspergillosis. The authors describe a case of a female patient with idiopathic bone marrow aplasia and disseminated fusariosis, who initially appeared to benefit from voriconazole and amphotericin B; however, due to persistent neutropenia, her clinical condition deteriorated with fatal evolution.
Item Description:0365-0596
10.1016/j.abd.2019.12.008