Keratinocytic epidermal nevus with ipsilateral breast hypoplasia
Breast hypoplasia has been reported in some epidermal nevus syndromes, but not with a keratinocytic epidermal nevus. Herein, we describe the first case of breast hypoplasia associated with a keratinocytic epidermal nevus. Keratinocytic epidermal nevi have been shown to be associated with somatic mut...
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| Main Authors: | , , |
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| Format: | Book |
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Wolters Kluwer,
2019-07-01T00:00:00Z.
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| Summary: | Breast hypoplasia has been reported in some epidermal nevus syndromes, but not with a keratinocytic epidermal nevus. Herein, we describe the first case of breast hypoplasia associated with a keratinocytic epidermal nevus. Keratinocytic epidermal nevi have been shown to be associated with somatic mutations in FGFR3, PIK3CA, and HRAS. We hypothesize that hypoplasia may be due to a local mutation in the FGFR3 gene or increased androgen receptors in affected breast tissue. The patient was treated with CO2 laser with good cosmetic outcome. Keywords: Keratinocytic epidermal nevus, ipsilateral breast hypoplasia, FGFR3 |
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| Item Description: | 2352-6475 10.1016/j.ijwd.2018.12.003 |