Lipoprotein (a): More than a bystander in the etiology of hypertension? A study on essential hypertensive patients not yet on treatment
Background: Hypertension (HTN) is a very common disorder with a substantial impact on public health because of its complications. Objectives: To study the association of serum lipoprotein(a) [Lp(a)] elevation with essential hypertension (eHTN). Patients and Methods: This study was conducted on a gro...
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| Main Authors: | , , |
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| Format: | Book |
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Society of Diabetic Nephropathy Prevention,
2013-01-01T00:00:00Z.
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| Summary: | Background: Hypertension (HTN) is a very common disorder with a substantial impact on public health because of its complications. Objectives: To study the association of serum lipoprotein(a) [Lp(a)] elevation with essential hypertension (eHTN). Patients and Methods: This study was conducted on a group of essential hypertensive patients. Laboratory exams consisting of serum creatinine and Lp(a) were measured. Results: Ninety five essential hypertensive patients were enrolled to the study. Serum LP (a) in patients was 46.5±20. In patients an inverse correlation between serum Lp(a) andcreatinine clearance was seen (r = -0.175 p<0.05). There was a significant correlation between serum Lp(a) and age (r =0.191 p<0.05) or duration of HTN (known duration of hypertension period) (r =0.362 p<0.05). Conclusions: Our data suggest that Lp(a) may be involved as a cofactor in essential hypertension, with a mechanism that remains to be elucidated. |
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| Item Description: | 2251-8363 2251-8819 10.5812/nephropathol.9092 |