The Role of Immunotherapy in Multiple Myeloma

Multiple myeloma is the second most common hematologic malignancy. The treatment of this disease has changed considerably over the last two decades with the introduction to the clinical practice of novel agents such as proteasome inhibitors and immunomodulatory drugs. Basic research efforts towards...

Full description

Saved in:
Bibliographic Details
Main Authors: Mehmet Kocoglu (Author), Ashraf Badros (Author)
Format: Book
Published: MDPI AG, 2016-01-01T00:00:00Z.
Subjects:
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

MARC

LEADER 00000 am a22000003u 4500
001 doaj_761cb1bd0c9845bc8df89d5fc912b3e9
042 |a dc 
100 1 0 |a Mehmet Kocoglu  |e author 
700 1 0 |a Ashraf Badros  |e author 
245 0 0 |a The Role of Immunotherapy in Multiple Myeloma 
260 |b MDPI AG,   |c 2016-01-01T00:00:00Z. 
500 |a 1424-8247 
500 |a 10.3390/ph9010003 
520 |a Multiple myeloma is the second most common hematologic malignancy. The treatment of this disease has changed considerably over the last two decades with the introduction to the clinical practice of novel agents such as proteasome inhibitors and immunomodulatory drugs. Basic research efforts towards better understanding of normal and missing immune surveillence in myeloma have led to development of new strategies and therapies that require the engagement of the immune system. Many of these treatments are under clinical development and have already started providing encouraging results. We, for the second time in the last two decades, are about to witness another shift of the paradigm in the management of this ailment. This review will summarize the major approaches in myeloma immunotherapies. 
546 |a EN 
690 |a myeloma 
690 |a immunotherapy 
690 |a vaccines 
690 |a tumor antigens 
690 |a antibodies 
690 |a CAR-T 
690 |a adoptive cell therapy 
690 |a Medicine 
690 |a R 
690 |a Pharmacy and materia medica 
690 |a RS1-441 
655 7 |a article  |2 local 
786 0 |n Pharmaceuticals, Vol 9, Iss 1, p 3 (2016) 
787 0 |n http://www.mdpi.com/1424-8247/9/1/3 
787 0 |n https://doaj.org/toc/1424-8247 
856 4 1 |u https://doaj.org/article/761cb1bd0c9845bc8df89d5fc912b3e9  |z Connect to this object online.