Cyclosporine A Induces Cardiac Developmental Toxicity in Zebrafish by Up-Regulation of Wnt Signaling and Oxidative Stress

Due to the widely application of Cyclosporine A (CsA) as an immunosuppressant in clinic, it is necessary to study its potential toxicity. Therefore, we used zebrafish as a model animal to evaluate the toxicity of CsA on embryonic development. Exposure of zebrafish embryos to CsA at concentrations of...

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Main Authors: Mengqi Wan (Author), Ling Huang (Author), Jieping Liu (Author), Fasheng Liu (Author), Guilan Chen (Author), Huiwen Ni (Author), Guanghua Xiong (Author), Xinjun Liao (Author), Huiqiang Lu (Author), Juhua Xiao (Author), Qiang Tao (Author), Zigang Cao (Author)
Format: Book
Published: Frontiers Media S.A., 2021-11-01T00:00:00Z.
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