Pharmacogenomic profile of actionable molecular variants related to drugs commonly used in anesthesia: WES analysis reveals new mutations

• Main Authors: Juan Fernando Parada-Márquez (Author), Nicolás David Maldonado-Rodriguez (Author), Paula Triana-Fonseca (Author), Nora Constanza Contreras-Bravo (Author), Carlos Alberto Calderón-Ospina (Author), Carlos M. Restrepo (Author), Adrien Morel (Author), Oscar Javier Ortega-Recalde (Author), Daniel Felipe Silgado-Guzmán (Author), Mariana Angulo-Aguado (Author), Dora Janeth Fonseca-Mendoza (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Genetic interindividual variability is associated with adverse drug reactions (ADRs) and affects the response to common drugs used in anesthesia. Despite their importance, these variants remain largely underexplored in Latin-American countries. This study describes rare and common varian...