β-catenin ISGylation promotes lipid deposition and apoptosis in ethanol-stimulated liver injury models

• Main Authors: Qi Ding (Author), Guodong Zhang (Author), Yang Wang (Author), Lei Xu (Author), Meifei Wu (Author), Yiwen Zhou (Author), Tao Xu (Author), Xiaoming Meng (Author), Cheng Huang (Author), Lei Zhang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background The restoration of the Wnt/β-catenin pathway to alleviate alcoholic fatty liver disease (AFLD) progression is under study as a new strategy for alcoholic liver disease (ALD) treatment. Recent studies have indicated that interferon-stimulated gene 15 (ISG15) can covalently bind to β-cateni...