Improving Editing Efficiency for the Sequences with NGH PAM Using xCas9-Derived Base Editors
The development of CRISPR/Cas9-mediated base editors (BEs) provided a versatile tool for precise genome editing. The recently developed xCas9-derived base editors (xBEs) that recognize the NG PAM substantially expand the targeting scope in the genome, while their editing efficiency needs to be impro...
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Main Authors: | Xinyi Liu (Author), Guanglei Li (Author), Xueliang Zhou (Author), Yunbo Qiao (Author), Ruixuan Wang (Author), Shaohui Tang (Author), Jianqiao Liu (Author), Lisheng Wang (Author), Xingxu Huang (Author) |
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Format: | Book |
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Elsevier,
2019-09-01T00:00:00Z.
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