Hemorrhagic Shock Induces a Rapid Transcriptomic Shift of the Immune Balance in Leukocytes after Experimental Multiple Injury

• Main Authors: Lisa Debler (Author), Annette Palmer (Author), Sonja Braumüller (Author), Bettina Klohs (Author), Tom Eirik Mollnes (Author), Karlheinz Holzmann (Author), Markus Huber-Lang (Author), Rebecca Halbgebauer (Author)
• Format: Book
• Published: Hindawi Limited, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The immune response following trauma represents a major driving force of organ dysfunction and poor outcome. Therefore, we investigated the influence of an additional hemorrhagic shock (HS) on the early posttraumatic immune dysbalance in the whole population of blood leukocytes. A well-established m...