Marked attenuation of inflammatory mediator-induced C-fiber sensitization for mechanical and hypotonic stimuli in TRPV4<sup>-/- </sup>mice
<p>Abstract</p> <p>Inflammatory mediators can directly sensitize primary afferent nociceptors to mechanical and osmotic stimuli. Sensitized nociceptors have a lowered threshold of activation and increased spontaneous activity, which result in symptoms of hyperalgesia and pain, resp...
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| Main Authors: | , , |
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| Format: | Book |
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SAGE Publishing,
2007-10-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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