Tethered Aryl Groups Increase the Activity of Anti-Proliferative Thieno[2,3-<i>b</i>]Pyridines by Targeting a Lipophilic Region in the Active Site of PI-PLC
The compounds 2-amino-3-carboxamido-thieno[2,3-<i>b</i>]pyridines have demonstrated excellent anti-proliferative activity against human cancer cell lines, including the triple-negative breast cancer cell line MDA-MB-231. In this study, 81 novel thieno[2,3-<i>b</i>]pyridines w...
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| Main Authors: | , , , |
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| Format: | Book |
| Published: |
MDPI AG,
2021-11-01T00:00:00Z.
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