Wogonin Inhibits Cardiac Hypertrophy by Activating Nrf-2-Mediated Antioxidant Responses

• Main Authors: Xiaowen Shi (Author), Bin Zhang (Author), Zhenliang Chu (Author), Bingjiang Han (Author), Xueping Zhang (Author), Ping Huang (Author), Jibo Han (Author)
• Format: Book
• Published: Hindawi-Wiley, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Cardiac hypertrophy is one of the initial disorders of the cardiovascular system and can induce heart failure. Oxidative stress is an important pathophysiological mechanism of cardiac hypertrophy. Wogonin (Wog), an important flavonoid derived from the root of Scutellaria baicalensis Geor...