Immunogenicity and protective efficacy of recombinant Bacille Calmette-Guerin strains expressing mycobacterium antigens Ag85A, CFP10, ESAT-6, GM-CSF and IL-12p70

• Main Authors: Fu-Ying Dai (Author), Jun-Fang Wang (Author), Xue-Li Gong (Author), Lang Bao (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: This study aimed to evaluate the immunogenicity and protective efficacy of recombinant bacille calmette-guerin (rBCG) strains expressing Ag85A (A), CFP10 (C), ESAT6 (E), IL-12p70 (I), and fusion protein GM-CSF (G). Method: rBCGs were established by integrating of A, C, E, I, G, AE, CE, IE...