Formulation and evaluation of transparent ibuprofen soft gelatin capsule

The compound ibuprofen, 2-(4-isobutylphenyl) propionic acid, has been known e.g. from Martindale, the Extra Pharmacopoeia, 28 th edition, 1982, p.256, as a drug which had anti-inflammatory and analgesic properties. It is used for the treatment of rheumatoid arthritis or other inflammatory diseases o...

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Main Authors: A Lodha (Author), A Patel (Author), J Chaudhuri (Author), P Jadia (Author), T Joshi (Author), J Dalal (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2012-01-01T00:00:00Z.
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042 |a dc 
100 1 0 |a A Lodha  |e author 
700 1 0 |a A Patel  |e author 
700 1 0 |a J Chaudhuri  |e author 
700 1 0 |a P Jadia  |e author 
700 1 0 |a T Joshi  |e author 
700 1 0 |a J Dalal  |e author 
245 0 0 |a Formulation and evaluation of transparent ibuprofen soft gelatin capsule 
260 |b Wolters Kluwer Medknow Publications,   |c 2012-01-01T00:00:00Z. 
500 |a 0975-7406 
500 |a 0976-4879 
500 |a 10.4103/0975-7406.94154 
520 |a The compound ibuprofen, 2-(4-isobutylphenyl) propionic acid, has been known e.g. from Martindale, the Extra Pharmacopoeia, 28 th edition, 1982, p.256, as a drug which had anti-inflammatory and analgesic properties. It is used for the treatment of rheumatoid arthritis or other inflammatory diseases of joints, soft tissue rheumatism and gout. Ibuprofen, because of its analgesic properties, has been widely used as anodyne, e.g. against pain or discomfort associated with headache, toothache or menstruation. A medication suitable to combat acute pain is demanded to display its effects fast which action, in turn, is only achieved by a quick release and good bio-availability of the active-ingredient. It is for the commercial forms in particular that the conditions of preparation must be strictly observed, as minor alterations in production procedures such as mixing, pressure of compression and type of machine will affect the physical properties of the particles of he active ingredient and will deteriorate its bio-availability. It is an object of this presentation to provide a medicament that can be readily taken that contains an active amount of ibuprofen in a carrier, that is simple to prepare and that will quickly display a high activity. 
546 |a EN 
690 |a Ibuprofen 
690 |a anti-inflammatory 
690 |a Pharmacy and materia medica 
690 |a RS1-441 
690 |a Analytical chemistry 
690 |a QD71-142 
655 7 |a article  |2 local 
786 0 |n Journal of Pharmacy and Bioallied Sciences, Vol 4, Iss 5, Pp 95-97 (2012) 
787 0 |n http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2012;volume=4;issue=5;spage=95;epage=97;aulast=Lodha 
787 0 |n https://doaj.org/toc/0975-7406 
787 0 |n https://doaj.org/toc/0976-4879 
856 4 1 |u https://doaj.org/article/7753d2f1888f44f1906b53b8c27e5ad0  |z Connect to this object online.