Application of Size and Maturation Functions to Population Pharmacokinetic Modeling of Pediatric Patients

• Main Authors: Hyun-moon Back (Author), Jong Bong Lee (Author), Nayoung Han (Author), Sungwoo Goo (Author), Eben Jung (Author), Junyeong Kim (Author), Byungjeong Song (Author), Sook Hee An (Author), Jung Tae Kim (Author), Sandy Jeong Rhie (Author), Yoon Sun Ree (Author), Jung-woo Chae (Author), JaeWoo Kim (Author), Hwi-yeol Yun (Author)
• Format: Book
• Published: MDPI AG, 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Traditionally, dosage for pediatric patients has been optimized using simple weight-scaled methods, but these methods do not always meet the requirements of children. To overcome this discrepancy, population pharmacokinetic (PK) modeling of size and maturation functions has been proposed. The main o...