The strange case of a patient affected by acromegaly with osteoporomalacia without hypogonadism
Acromegaly is a rare disease that, in the majority of cases, is due to the presence of a benign growth hormone (GH)- producing tumor of the pituitary. Growth hormone has profound effects on linear bone growth, bone metabolism, and bone mass. In acromegaly, the skeletal effects of chronic GH excess h...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
PAGEPress Publications,
2011-09-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | Acromegaly is a rare disease that, in the majority of cases, is due to the presence of a benign growth hormone (GH)- producing tumor of the pituitary. Growth hormone has profound effects on linear bone growth, bone metabolism, and bone mass. In acromegaly, the skeletal effects of chronic GH excess have been mainly addressed by evaluating bone mineral density (BMD). Most data were obtained in patients with active acromegaly, and apparently high or normal BMD was observed in the absence of hypogonadism. The Autors describe a case of patient affected by acromegaly without hypogonadism with serious osteoporosis and biological signs of osteomalacia. |
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| Item Description: | 10.4081/reumatismo.2005.291 0048-7449 2240-2683 |