Acute Genital Ulcers in a Woman Secondary to COVID-19 Infection: A Case Report

Jia Zhang,1,* Danni Wang,1,* Mingjing Chen,1 Jiajun Li,2 Wenxiang Huang1 1Department of Geriatrics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China; 2Department of Infectious Diseases, the First Affiliated Hospital of Chongqin...

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Main Authors: Zhang J (Author), Wang D (Author), Chen M (Author), Li J (Author), Huang W (Author)
Format: Book
Published: Dove Medical Press, 2024-01-01T00:00:00Z.
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Summary:Jia Zhang,1,* Danni Wang,1,* Mingjing Chen,1 Jiajun Li,2 Wenxiang Huang1 1Department of Geriatrics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China; 2Department of Infectious Diseases, the First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China*These authors contributed equally to this workCorrespondence: Wenxiang Huang, Department of Geriatrics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China, Tel +86 13883533808, Email wenxiang_huang@163.comAbstract: Acute genital ulcers (AGU) have been associated with various pathogens, such as Epstein-Barr virus (EBV) and cytomegalovirus (CMV). However, cases of AGU associated with coronavirus disease 2019 (COVID-19) are rare, and this disease significantly impairs human quality of life. In this case, we report a 37-year-old woman who presented with a five-day history of a painful genital ulcer and fever. A month earlier, she had experienced a COVID-19 infection that resolved without medical therapy. Physical examination revealed that multiple asymmetric ulcers presented on labia minora covered with whitish exudates. The patient, without any high-risk sexual behavior, or a personal or family history of autoimmune disorders or inflammatory bowel disease, was diagnosed with COVID-19-related AGU after ruling out other infectious and immune diseases. Following a two-week treatment of oral prednisone, her vulvar edema, ulcers, and fever improved significantly. This case suggests that AGU may be triggered by a COVID-19 infection.Keywords: COVID-19, SARS-CoV-2, acute genital ulcers, fever
Item Description:1178-7015